Approximately half a million Americans are affected by ulcerative colitis (UC)—a chronic disease that affects the colon or large intestine. If you're already taking medication to control your moderately to severely active UC and are still experiencing symptoms, including cramping; weight loss; fatigue; and frequent, loose, or bloody stools, it's likely that your UC is not sufficiently under control. Ask your doctor if REMICADE® is a treatment option that can help you.
REMICADE® can reduce signs and symptoms, induce and maintain remission, promote intestinal healing, and reduce or stop the need for steroids in adult patients with moderately to severely active UC who haven't responded well to other therapies. It works differently from conventional medications, targeting specific proteins in the body's immune system to help control inflammation.
Even when you are not flaring, UC can still cause damaging inflammation to the intestinal lining of the colon. In clinical studies, many people treated with REMICADE® experienced intestinal healing. Individual results may vary.
So if your current therapy isn't giving you enough relief from flares and the signs and symptoms of UC, ask your doctor if REMICADE® may be right for you.
Only your doctor can recommend a course of treatment after checking your health condition. REMICADE® (infliximab) can cause serious side effects such as lowering your ability to fight infections. Some patients, especially those 65 years and older, have had serious infections caused by viruses, fungi or bacteria that have spread throughout the body, including tuberculosis (TB) and histoplasmosis. Some of these infections have been fatal. Your doctor should monitor you closely for signs and symptoms of TB during treatment with REMICADE®.
Unusual cancers have been reported in children and teenage patients taking TNF-blocker medicines. Hepatosplenic T-cell lymphoma, a rare form of fatal lymphoma, has occurred mostly in teenage or young adult males with Crohn’s disease or ulcerative colitis who were taking REMICADE® and azathioprine or 6-mercaptopurine. For children and adults taking TNF blockers, including REMICADE®, the chances of getting lymphoma or other cancers may increase.
You should discuss any concerns about your health and medical care with your doctor.
What should I tell my doctor before I take REMICADE®?
You should let your doctor know if you have or ever had any of the following:
Also tell your doctor if you:
What should I watch for and talk to my doctor about before or while taking REMICADE®?
The following serious (sometimes fatal) side effects have been reported in people taking REMICADE®.
You should tell your doctor right away if you have any of the signs listed below:
You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.