If you're one of the half-million people with CD you know all too well how this condition can affect your life. CD is a chronic and serious condition  that causes inflammation of the digestive (or gastrointestinal [GI]) tract. Although it may involve any area of the GI tract, it usually affects the small intestine or colon.
People with CD typically experience periods when symptoms worsen and persist, called a "flare," which alternate with periods when the disease is inactive (few or no symptoms), called "remission". However, even when the disease is inactive, CD does not really go away . Sooner or later another flare will occur. This cycle of flares is common for people with CD. The main goals of treatment  are to reach and then maintain remission.
For patients with moderately to severely active CD, who haven't responded well to other therapies, REMICADE® may help . REMICADE® is a biologic, which is part of a class of advanced treatments . REMICADE® can help you gain long-lasting control over symptoms and flares, as shown in a 1-year clinical study.
REMICADE® can reduce signs and symptoms and induce and maintain remission in patients with moderately to severely active CD who haven't responded well to other therapies.
Only your doctor can recommend a course of treatment after checking your health condition. REMICADE® (infliximab) can cause serious side effects such as lowering your ability to fight infections. Some patients, especially those 65 years and older, have had serious infections caused by viruses, fungi or bacteria that have spread throughout the body, including tuberculosis (TB) and histoplasmosis. Some of these infections have been fatal. Your doctor should monitor you closely for signs and symptoms of TB during treatment with REMICADE®.
Unusual cancers have been reported in children and teenage patients taking TNF-blocker medicines. Hepatosplenic T-cell lymphoma, a rare form of fatal lymphoma, has occurred mostly in teenage or young adult males with Crohn’s disease or ulcerative colitis who were taking REMICADE® and azathioprine or 6-mercaptopurine. For children and adults taking TNF blockers, including REMICADE®, the chances of getting lymphoma or other cancers may increase.
You should discuss any concerns about your health and medical care with your doctor.
What should I tell my doctor before I take REMICADE®?
You should let your doctor know if you have or ever had any of the following:
Also tell your doctor if you:
What should I watch for and talk to my doctor about before or while taking REMICADE®?
The following serious (sometimes fatal) side effects have been reported in people taking REMICADE®.
You should tell your doctor right away if you have any of the signs listed below:
You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.