Psoriatic arthritis and REMICADE®
Your immune system works around the clock to protect your body from bacteria, viruses, and other foreign agents. When you have psoriatic arthritis, your immune system becomes overactive and produces excess amounts of a protein called tumor necrosis factor-alpha, or TNF-alpha.
The presence of excess TNF-alpha causes your immune system to mistakenly attack healthy joint cells. This leads to the inflammation or swelling and other symptoms you may experience with psoriatic arthritis. REMICADE® has been shown to block the action of TNF-alpha. This inhibits an underlying cause of inflammation.
Managing your psoriatic arthritis
Psoriatic arthritis is a condition that affects both the skin and the joints. Skin symptoms include plaques consisting of thick, raised areas of the skin, scaling, and redness. Joint symptoms include pain, stiffness, and swelling, which may affect your ability to do everyday tasks, like getting out of bed and getting dressed. While symptoms may differ from person to person, the joint damage caused by psoriatic arthritis is permanent.
Many doctors recognize the importance of helping to stop the progression of joint damage in their patients with active psoriatic arthritis. However, it's important to keep in mind that biologics are medicines that affect your immune system, and can cause serious side effects.
Talk to your doctor to find out if treatment with prescription REMICADE®, along with methotrexate, is right for you.
REMICADE® can help
In clinical studies, REMICADE®, when given with or without methotrexate, has been shown to:
- Work quickly to help relieve the pain, stiffness, and swelling of psoriatic arthritis—in as little as 2 weeks for some people
- Help stop further joint damage caused by psoriatic arthritis. For some people, it may help stop damage before it starts
Provide improvement in skin symptoms, including plaque thickness, scaling, and redness
— In one study, most people saw a reduction in skin symptoms of at least 75%
Individual results may vary.